[INTENDED USE]

The ToRCH Toxo/Rubella/CMV/HSV1/2 IgG/IgM Rapid Test Cassette is a

lateral flow chromatographic immunoassay for the qualitative detection of

antibodies (IgG and IgM) to Toxoplasma gondii (Toxo), Rubella virus

(Rubella), Cytomegalovirus (CMV) and Herpes simplex virus 1/2 (HSV 1/2)

in human Whole Blood/Serum/Plasma. It provides an aid in the diagnosis of

infection with ToRCH .

[SUMMARY]

ToRCH is an acronym for a group of infectious diseases that, while infecting

the pregnant women, may cause birth defects in their newborns. ToRCH

stands for 4 different infections that can adversely affect the pregnant

women and the fetus, newborn children including birth defects and often

leading to abortion. The four infections are Toxomplasma gondii (A

spirochete), Rubella (Virus), CMV-Cytomegalovirus (Virus),

HSV1/2-Herpes Simplex Virus 1/2. The infections usually cause few, if any,

symptoms in the pregnant woman, but pose greater risks of serious birth

defects for neonates. Infections caused by ToRCH -Toxoplasma, Rubella

Virus, Cytomegalo Virus (CMV) and Herpes Simplex Virus (HSV)-is the

major cause of BOH (Bad Obstetric History). Risks are severe, if the mother

gets the infection in the first trimester as the baby's organs start to form in

this stage. General symptoms include premature birth, growth

retardation,neurological abnormalities, damage of the eye, liver, heart and

ear as well as bone lesions. Microcephaly,hydrocephaly, seizures and

psychomotor retardation accompany these malformations.